Powerpuff Girls, The Summary ()

Ace
Hidden Character
Portrayed by Jeff Bennett
Unlocked upon defeat in Story Mode.

Big Billy
Playable Character
Portrayed by Jeff Bennett

cyclopean	eyes_closed	giant
green_skin	midriff	overweight

Blossom
Playable Character
Portrayed by Catherine Cavadini

artificial_life	child	hair_bow
ice_control	longhair	pink_outfit

Bubbles
Playable Character
Portrayed by Tara Strong

artificial_life	blue_outfit	child
eyebeams	sound_control	twintails

Buttercup
Playable Character
Portrayed by E.G. Daily

Fuzzy Lumpkins
Unlockable Character
Portrayed by Jim Cummings
Unlocked upon defeat in Story Mode.

HIM
Boss Character
Portrayed by Tom Kane
Final boss. Fought after beating Mojo Jojo as all three Powerpuff Girls. Unlocked upon defeat in Story Mode.

Mojo Jojo
Boss Character
Portrayed by Roger L. Jackson
First boss. Unlocked upon defeat in Story Mode.

animal_kingdom	caped	firearms
green_skin	partial_helmet	primate

Princess
Playable Character
Portrayed by Jennifer Hale

Sedusa
Playable Character
Portrayed by Jennifer Hale